CTRI/2022/09/045528
Not yet recruiting
Phase 2
Effect of dexmedetomidine infusion on post operative cognitive dysfunction in elderly patients after oral cancer surgery and its correlation with ADRA2A genotype: A double blinded randomized controlled study
Department of Anaesthesiology0 sites0 target enrollmentTBD
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx
- Sponsor
- Department of Anaesthesiology
- Status
- Not yet recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients giving written informed consent will be taken. Aged between 50\-75years. ASA physiological I and II.
Exclusion Criteria
- •Refusal of patients
- •Patients undergone General anesthesia within 7 days, had taken Alpha\-2 agonist within 14 days.
- •Patients who had experienced acute stable angina or myocardial infarcation within previous 6 week.
- •Patients with liver cirrhosis, thrombocytopenia and coagulopathies ,third degree heart block and who had contraindication of neuraxial block, severe bradycardia and has systolic blood pressure less than 90 mmhg.
- •Pregnant female
- •Current psychiatric disorder h/o seizures
- •Known drug allergy to the study.
- •ASA III and ASA IV.
Outcomes
Primary Outcomes
Not specified
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