Release of mitochondrial DNA in patients undergoing cardiac surgery with and without ischemic preconditioning

Not Applicable

• Conditions: I25.9; Chronic ischaemic heart disease, unspecified

• Registration Number: DRKS00009418
• Lead Sponsor: niversitätsklinikum Essen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2012-10-01
• Study Start: 2015-10-14
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 65

Inclusion Criteria

Cardiac Surgery, informed consent

Exclusion Criteria

Combined CABG and valve surgery

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
iberation of mitochondrial DNA, prior to induction of anesthesia, before and after ischemic preconditioning as well as before and after cardiopulmonary bypass.

Secondary Outcome Measures

Name	Time	Method
Immunparalyses, i.e. liberation of mitochondrial DNA, at the time points analyzed as mentioned in the primary outcome section.