Which is better in management of increased intra cranial pressure among children, hypertonic (3%) saline (NaCl) or mannitol? An Experimental Study
Not Applicable
- Conditions
- Health Condition 1: G934- Other and unspecified encephalopathy
- Registration Number
- CTRI/2019/04/018788
- Lead Sponsor
- Veer Surendra Sai Institute of Medical Sciences and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Children admitted to our hospital with clinical symptoms and signs suggestive of raised intracranial pressure
Exclusion Criteria
Children with 1.Compromised renal function
2.Hepatic encephalopathy
3.Serum Na+ (.150meq/L)
4.Diabetic ketoacidosis
5.Cerebral malaria
6.Low blood pressure as per the age
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To find out the efficacy of hypertonic saline vs mannitol in decreasing mean arterial pressureTimepoint: AT 0 HOUR, 24 HOUR, 72 HOUR
- Secondary Outcome Measures
Name Time Method 1. To find out the incidence of electrolyte imbalance (Na, K) between two groups <br/ ><br>2.To find out the morbidity and mortality between two groupsTimepoint: 1. Estimation of serum Na and serum K at 0, 24, 72 hour of hospitalisation <br/ ><br>2. Duration of hospitalisation in days till discharge or death from hospital