Long Term Cardiovascular Complications in Men With Obstructive Sleep Apnea

• Conditions: Obstructive Sleep Apnea; Cardiovascular Diseases; Metabolic Diseases

• Registration Number: NCT01475682
• Lead Sponsor: The University of Hong Kong

Brief Summary

Subjects with Obstructive Sleep Apnea (OSA) are at increased risk of developing cardiometabolic complications, and effective long-term nCPAP treatment significantly reduces the risk of cardiovascular morbidity and mortality.

Detailed Description

1. Primary outcome:

Incidence of cardiometabolic diseases in subjects with OSA over 9 years.

2. Secondary outcomes:

Effects of CPAP treatment on cardiometabolic conditions

Study Timeline

• Study Start: 2011-11
• Study First Submitted: 2011-11-16
• Study First Submitted QC: 2011-11-18
• Study First Posted: 2011-11-21
• Status Verified: 2014-07
• Last Update Submitted: 2014-07-16
• Last Update Posted: 2014-07-17
• Primary Completion: 2015-05
• Study Completion: 2015-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: 167

Inclusion Criteria

• From previous cohort for reassessment.

Exclusion Criteria

• Unstable medical conditions

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of cardiometabolic complications	9 years	167 subjects recruited from our previous "OSA and metabolic syndrome" (OSAMS) cohort from October 2002 to June 2007 will be invited to be reassessed at this time point.

Secondary Outcome Measures

Name	Time	Method
Effects of CPAP treatment on cardiometabolic conditions	9 years

Trial Locations

Locations (1)

Queen Mary Hospital; 🇭🇰 Hong Kong, Hong Kong