Is Sheep Ghee Cardioprotective?

Not Applicable

Completed

• Conditions: Inflammation; Cholesterol; Metabolic Disorder
• Interventions: Dietary Supplement: sunflower oil; Dietary Supplement: sheep ghee

• Registration Number: NCT05492279
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Normal volunteers were randomly received Sheep ghee or sunflower oil, and before and after the study lipid profile and HS-CRP were measured.

Detailed Description

During outpatient clinic visits, potentially eligible individuals were screened for enrollment according to the inclusion and exclusion criteria.

Patients were randomly allocated into the treatment and control groups via the blocked randomization method.

The control group received a normal diet for eight weeks with 10 g of sunflower oil. In the treatment group, sunflower oil was replaced with 10 g of sheep ghee.

50 patients in each group were enrollment. Patients' information, including demographic data and the serum levels of fasting blood sugar (FBS), LDL, HDL, triglyceride (TG), and hs-CRP, were recorded in datasheets twice: once before treatment with sheep ghee and once eight weeks later.

Study Timeline

• Study Start: 2020-02-01
• Primary Completion: 2022-06-01
• Study Completion: 2022-07-01
• Status Verified: 2022-08
• Study First Submitted: 2022-08-05
• Study First Submitted QC: 2022-08-05
• Last Update Submitted: 2022-08-05
• Study First Posted: 2022-08-08
• Last Update Posted: 2022-08-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• healthy adults, seeking outpatient visit at professor kojuri cardiology clinic

Exclusion Criteria

• any history of ischemic heart disease (IHD),
• coronary artery bypass grafting (CABG)
• percutaneous intervention (PCI)
• stroke
• peripheral vascular diseases
• use of anti-hyperlipidemic agents
• unwillingness to participate.
• Need of tight hyperlipidemia control.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
control group	sunflower oil	10 gr sunflower oil
intervention	sheep ghee	10 gr Sheep ghee

Primary Outcome Measures

Name	Time	Method
HDL cholesterol	2 months	Serum HDL in mg/dl
LDL cholesterol	2 months	serum LDL level in mg/dl
total cholesterol	2 months	serum total cholesterol in mg/dl
HS-CRP	2 months	HS-CRP level in picogram/dl

Secondary Outcome Measures

Name	Time	Method
adverse effect	2 months	gastrointestinal, skin, allergy

Trial Locations

Locations (1)

Javad Kojuri; 🇮🇷 Shiraz, Fars, Iran, Islamic Republic of