Microvascular Decompression for Unilateral Pulsatile Tinnitus- A Prospective Randomised Multicenter Study

Not Applicable

• Conditions: Pulsatile tinnitus secondary to vascular compression of vestibulocochlear nerve; Neurological - Other neurological disorders

• Registration Number: ACTRN12622000838718
• Lead Sponsor: Monash Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-06-15
• Last Update Posted: 20 June 2022

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

The inclusion criteria are as follows: 1) age 18-75 years; 2) unilateral pulsatile tinnitus with some preservation of ipsilateral hearing; 3) MRI brain with no alternative major abnormality accounting for symptoms and there is identifiable vascular compression of the vestibulocochlear nerve; 4) all conservative therapies have been trialled and exhausted without significant symptom relief; 5) pre-op assessment by audiometry, vestibular testing and assessment by either a consultant ENT surgeon or Neurosurgeon who deem that microvascular decompression (MVD) is indicated; 6) patients with an American Society of Anaesthiology (ASA) score of I/II; and 7) patients have suffered from pulsatile tinnitus for >12 months

Exclusion Criteria

The exclusion criteria are as follows: 1) non-pulsatile tinnitus; 2) bilateral tinnitus; 3) abnormal MRI brain with significant structural abnormality; 4) previous retrosigmoid craniotomy or radiotherapy to the posterior fossa of the brain; 5) severe medical co-morbidities with ASA score III/IV; 6) patients with psychiatric comorbidity; 7) total deafness; and 8) inability to consent.

Study & Design

• Study Type: Interventional
• Study Design: Not specified