Study on uterine fibroid with vitamin D and prolactin.

Not Applicable

Conditions: Health Condition 1: - Health Condition 2: O262- Pregnancy care for patient with recurrent pregnancy loss

Registration Number: CTRI/2022/09/045404

Lead Sponsor: ot Applicable

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

Inclusion criteria for case:

1.Female subjects with 18 to 50 years of age (both inclusive) who are in pre-menopausal status.

2.Documented evidence of atleast one uterine fibroid lesion of 2 cm3 or greater on ultrasonography.

3.Willing to participate in the study.

Inclusion criteria for control:

1.Female subjects with 18 to 50 years of age (both inclusive) who are in pre-menopausal status.

2.Documented evidence of no uterine fibroid lesion on ultrasonography.

3.Willing to participate in the study.

Exclusion Criteria

Exclusion criteria for both cases and controls:

1.Pregnant and lactating women.

2.Women with a history of abortion or miscarriage in the last 6 months.

3.Women with a history of prior surgery for fibroids (myomectomy) or hysterectomy.

4.Women with concomitant use of vitamin D supplements or history of vitamin D supplement within the last 3 months.

5.Women with concomitant use of hormonal treatment (including oral contraceptives) or history of hormonal treatment within the last 3 months.

6.Women with concomitant use of drug known to increase the serum prolactin levels [e.g., haloperidol, chlorpromazine, thioridazine, thiothixene (typical antipsychotics); risperidone, amisulpride, molindone, zotepine (atypical antipsychotics); sertraline, fluoxetine, paroxetine, pargyline, clorgyline (antidepressants); buspirone, alprazolam (psychotropics); metoclopramide and domperidone (prokinetics), alpha-methyldopa, reserpine and verapamil (antihypertensive), morphine (opiates)].

7.Women with diabetes mellitus, pituitary, and hypothyroidism, chronic renal failure, or psychiatric disease

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The association of serum levels of Vitamin D3 and Prolactin will be evaluated in Patients with uterine fibroids and it will compare with healthy individuals.Timepoint: 12 Weeks

Secondary Outcome Measures