Clinical study to assess the association of vitamin D and prolactin with uterine fibroid in premenopausal women - NA

ot Applicable0 个研究点目标入组 0 人开始时间: 待定最近更新: 2022年10月17日

试验速览

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•Inclusion criteria for case:
•1.Female subjects with 18 to 50 years of age (both inclusive) who are in pre-menopausal status.
•2.Documented evidence of atleast one uterine fibroid lesion of 2 cm3 or greater on ultrasonography.
•3.Willing to participate in the study.
•Inclusion criteria for control:
•1.Female subjects with 18 to 50 years of age (both inclusive) who are in pre-menopausal status.
•2.Documented evidence of no uterine fibroid lesion on ultrasonography.
•3.Willing to participate in the study.

•Exclusion criteria for both cases and controls:
•1.Pregnant and lactating women.
•2.Women with a history of abortion or miscarriage in the last 6 months.
•3.Women with a history of prior surgery for fibroids (myomectomy) or hysterectomy.
•4.Women with concomitant use of vitamin D supplements or history of vitamin D supplement within the last 3 months.
•5.Women with concomitant use of hormonal treatment (including oral contraceptives) or history of hormonal treatment within the last 3 months.
•6.Women with concomitant use of drug known to increase the serum prolactin levels [e.g., haloperidol, chlorpromazine, thioridazine, thiothixene (typical antipsychotics); risperidone, amisulpride, molindone, zotepine (atypical antipsychotics); sertraline, fluoxetine, paroxetine, pargyline, clorgyline (antidepressants); buspirone, alprazolam (psychotropics); metoclopramide and domperidone (prokinetics), alpha-methyldopa, reserpine and verapamil (antihypertensive), morphine (opiates)].
•7.Women with diabetes mellitus, pituitary, and hypothyroidism, chronic renal failure, or psychiatric disease

发起方