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Impact of intestinal dysbiosis in acute pancreatitis

Not Applicable
Recruiting
Conditions
acute pancreatitis
Registration Number
JPRN-UMIN000050720
Lead Sponsor
Chiba University Hospital Emergency and Critical Care Medicine 1-8-1 Inohana, Chuo, Chiba 260-8677, Japan
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
60
Inclusion Criteria

Not provided

Exclusion Criteria

Patients with inflammatory bowel disease Patients with diarrhea prior to admission Patients who have received antimicrobial agents for more than 1 week in the 2 months prior to admission Patients who are judged to be inappropriate as research subjects by the principal investigator.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Changes in various parameters of the intestinal microbiota, protein concentration in stool, and metabolite concentration
Secondary Outcome Measures
NameTimeMethod
Relationship between each parameter and short- and long-term prognosis Correlation of each parameter with treatment details and clinical course during ICU stay Correlation between the amount of diarrhea and alpha-diversity parameters, protein concentration in each stool, and metabolite concentration Cluster analysis in patients with acute pancreatitis Development of artificial intelligence to predict patients' outcomes using collected clinical data and radiological information
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