Evaluation of Two Approaches in Enhancing the Efficacy of Inferior Alveolar Nerve Block During Treatment of Mandibular First Permanent Molars With Symptomatic Irreversible Pulpitis: A Randomized Parallel Controlled Trial
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 180
- Locations
- 1
- Primary Endpoint
- Pain assessment
Study Overview
Brief Summary
The study is designed as a randomized parallel controlled trial with three groups. Participants aged above 18 years with the first permanent molars with symptomatic signs of irreversible pulpitis will be randomly assigned into 3 groups. The first group (experimental group) will be injected with 4% articaine 1:100.000 epinephrine (inferior alveolar nerve block) will be anesthetized using 4% articaine 1:100.000 plus cryotherapy application, and the second group (experimental group) will be anaesthetised with IANB plus buccal infiltration. For the third group (control group), the mandibular molars will be anaesthetized using epinephrine using the inferior alveolar nerve block.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Supportive Care
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 19 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Patients aged above 18 years
- •Presence of at least one mandibular first permanent molar, with signs and symptoms of irreversible pulpititis
Exclusion Criteria
- •Participants with a history of taking medications that could interfere with the action of the anaesthetic solutions
- •Presence of paresthesia
- •Presence of psychological problems
- •Taking analgesics or other medications that would alter the inflammatory response of the pulp or provide analgesia 12 h pre-operatively
Outcomes
Primary Outcomes
Pain assessment
Time Frame: up to 24 hours
verbal rating scale (VRS) withh the following scores: Score 0: no pain, Score 1: mild pain, Score 2: moderate pain, and Score 3: severe pain.
Secondary Outcomes
No secondary outcomes reported
Investigators
Ahmad Elheeny
Assistant Professor
Minia University