SuperStarch Study

Not Applicable

• Conditions: Post-operative insulin resistance; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN45230380
• Lead Sponsor: East Lancashire Healthcare Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-06-18
• Last Update Posted: 27 February 2023
• Study Completion: 2023-09-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Patients >18 years
2. Laparoscopic colorectal resection
3. Included in Enhanced Recovery Protocol
4. American Society of Anesthesiologists (ASA) Physical Status classification 1-3
5. Able to give consent

Exclusion Criteria

1. Non-English speaker
2. Pregnancy
3. Diagnosed diabetes mellitus (diet, drug or insulin controlled).
4. Diagnosed impaired glucose tolerance (fasting glucose in POAC >5.5 mmol/l and/or HbA1C>5.7%)
5. Decreased gastrointestinal motility (from medication or disease) or predisposition to reflux
6. Diagnosis of inflammatory bowel disease
7. Allergy to either preoperative carbohydrate drink

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in insulin resistance from baseline on postoperative day 1 (POD 1) measured by Homeostasis Model Assessment (HOMA), which utilises serial fasting blood glucose and insulin measurements.