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Clinical Trials/NCT04082689
NCT04082689
Active, not recruiting
Not Applicable

Bowel And Bladder Function in Infant Toilet Training- a Randomized Intervention Study to Investigate the Efficacy of Assisted Infant Toilet Training on Preventing Functional Gastrointestinal and Urinary Tract Disorders up to 4 Years of Age

Dalarna County Council, Sweden6 sites in 1 country293 target enrollmentApril 18, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Infantile Colic
Sponsor
Dalarna County Council, Sweden
Enrollment
293
Locations
6
Primary Endpoint
Prevalence of infant colic
Status
Active, not recruiting
Last Updated
last year

Overview

Brief Summary

The overall purpose is to assess whether assisted infant toilet training during the first year of life can prevent functional gastrointestinal and urinary tract disorders up to 4 year of age. Healthy Swedish children will be randomized to start assisted infant toilet training at 0-2 months of age or at 10-11 months of age.

The toilet training process will be described including mother-to-infant attachment and parental stress.

Detailed Description

The mastery of toilet training is an important developmental milestone for children and parents. The age at which children start toilet training has increased during the last decades in the Western world. 50 years ago most children were out of nappies by 1,5 years of age. Today, wearing nappies by 3-4 years of age is considered normal. Meanwhile an increase in functional gastrointestinal and urinary tract disorders and toileting problems is reported by health care professionals. A randomized multicenter intervention study is conducted at Child Health Care Centers in Sweden to investigate whether assisted infant toilet training initiated during the first year of life can prevent functional bowel and bladder disorders.

Registry
clinicaltrials.gov
Start Date
April 18, 2019
End Date
September 2025
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Dalarna County Council, Sweden
Responsible Party
Principal Investigator
Principal Investigator

Barbro Hedin Skogman

Senior consultant at the Department of Paediatrics, Falun Hospital, Associate professor at Örebro Universitet, post-doctoral researcher at the Center for Clinical Research (CKF) Dalarna, Sweden

Dalarna County Council, Sweden

Eligibility Criteria

Inclusion Criteria

  • Full-term infant (born at gestational week 37+0 to 41+6)

Exclusion Criteria

  • Infants with malformations or disorders that may affect the gastrointestinal or urinary tract in any relevant way
  • Infants born small for gestational age (SGA), \< - 2 standard deviation
  • Parents with insufficient understanding of the Swedish language
  • Infants older than 2 months, 1 week and 6 days at inclusion

Outcomes

Primary Outcomes

Prevalence of infant colic

Time Frame: Up to 5 months of age

Infant colic measured with validated questionnaires according to the ROME IV criteria, including a prospective 24h infant behavioral diary when infant colic is suspected

Prevalence of infant dyschezia

Time Frame: Up to 9 months of age

Infant dyschezia, measured with validated questionnaires according to the ROME IV criteria

Prevalence of functional constipation

Time Frame: Up to 9 months of age

Functional constipation, measured with validated questionnaires according to the ROME IV criteria

Secondary Outcomes

  • Prevalence of stool toileting refusal(At 4 years of age)
  • Prevalence of functional constipation(Up to 4 years of age)
  • Prevalence of gastrointestinal symptoms(At 4 years of age)
  • Prevalence of bladder dysfunction(Up to 4 years of age.)

Study Sites (6)

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