Characterization of molecular-pathological pain-inducing tissue components in patients with lipedema
Recruiting
- Conditions
- E88.28
- Registration Number
- DRKS00030510
- Lead Sponsor
- niversitätsklinikum Köln
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
Lipedema: Diagnosis of lipedema, BMI < 30 kg/m2, waist < 80 cm;
Adiposity: BMI > 35 kg/m2, waist > 100 cm;
Normalweight non-lipedema: BMI < 30 kg/m2, waist < 80 cm
Exclusion Criteria
restrains in communication skills; diseases that affect the sensory nervous system, skin issitations at the testing areas; topical application of analgesics at the testing areas, alterations in pain perception or other diagnoses of chronic pain
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Characterization of the clinical phenotype by assessment of pressure pain threshold and vibration detection threshold by quantitativ sensory testing according to the protocol of the DFNS, as well as the Germain Pain Questionnaire
- Secondary Outcome Measures
Name Time Method Characterization of histological alterations of nociceptive skin innervation, characterization of alterations in cytokines and growth factors