NL-OMON51544已完成不适用
Brain and glycemic responses to soft drinks with different sweeteners (SWEETBRAIN) - Brain and glycemic responses to sweet soft drinks
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •- Age between 18 and 30 years
- •- BMI between 18.5 and 25 kg/m2
- •- Apparently healthy (self-reported)
- •- Right-handed
- •- Sufficient blood hemoglobin (Hb) levels (women > 7,5; men > 8.5 g/dl) and
- •having antecubital veins suitable for blood sampling via a catheter
- •- Willing to be informed about incidental findings of pathology and consenting
- •to informing their general practitioner about this.
排除标准
- •- Having disturbances of glucose metabolism such as being prediabetic or
- •- Use of medication that could influence study results including
- •insulin/metformin/proton pump inhibitors, antacids, anti-depressants
- •- Allergy or intolerance for any of the study products/compounds (sucrose,
- •sucralose, stevia extraxt, allulose, monk fruit extract)
- •- Being a regular smoker (smoking more than one cigarette or e-cigarette with
- •nicotin per day)
- •- Drinking more than 14 glasses of alcohol a week
- •- Having genetic, psychiatric or neurological diseases affecting the brain
- •- Gastric disorders or regular gastric complaints (more than once per week),
- •for example heart burn
- •- Having renal or hepatic disease
- •- Using recreational drugs more than once per week (e.g. marihuana, XTC, GHB,
- •laughing gas)
- •- Having given a blood donation in the past two months
- •- Being pregnant, lactating or planning on becoming pregnant during the study
- •- Currently following or having followed calorie-restricted diet in the past
- •- Participating in other research during the study period
- •- Not having a general practitioner
- •- Being an employee or student of the Division of Human Nutrition and Health
- •- Having a contra-indication to MRI scanning, including, but not limited to:
- •o Pacemakers and defibrillators
- •o Intraorbital or intraocular metallic fragments
- •o Other metal objects on/in the head which cannot be removed
- •o Ferromagnetic implants
- •o Claustrophobia
研究者
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