Clinical study on the treatment of allergic rhinitis with Chinese herbal medicine desensitization Zhixiao Decoction: a randomized controlled trial
- Conditions
- allergic rhinitis
- Registration Number
- ITMCTR2100004670
- Lead Sponsor
- Shanghai Dongfang Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion criteria
All the following conditions should be met for the included patients:
(1) Those who met the diagnostic criteria of moderate to severe persistent allergic rhinitis;
(2) According to the international diagnostic criteria (ARIA) of AR:
? Clinical symptoms: two or more symptoms such as sneezing, clear water like runny nose, nasal itching and nasal congestion, lasting or accumulating for more than 1 hour every day;
? Allergen test: at least one allergen SPT and / or serum specific IgE were positive.
(3) The TNSS score should be = 4.
(4) They were 18-65 years old;
(5) Informed consent, signed informed consent form, and volunteers.
Exclusion criteria
Those with one of the following conditions will be excluded from this study:
(1) Patients with acute sinusitis or respiratory tract infection in the past two weeks;
(2) Patients with bronchial asthma, moderate or above atopic dermatitis, immune diseases and severe chronic inflammatory diseases;
(3) History of drug allergy;
(4) Those who have received specific immunotherapy in the past two years, and those who have received anti allergic Chinese medicine, systemic hormone therapy or antihistamine therapy in the past two weeks;
(5) Pregnant or lactating patients.
(6) Severe lung, liver, kidney disease or other serious primary disease.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total nasal symptom scale (TNSS);
- Secondary Outcome Measures
Name Time Method Rhinitis Quality of Life Questionnaire, RQLQ;Detection of serum specific IgE level;