The effect of Vit D on AMH level and ovarian reserve in 18-40 years old female breast cancer patients who have been treated with chemotherapy between 1397-1398 in Imam Khomeini hospital.
Phase 3
Recruiting
- Conditions
- Infertility due to breast cancer chemotherapy..
- Registration Number
- IRCT20180718040514N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 40
Inclusion Criteria
Chemotherapy candidate Breast cancer patients between 18-40 years- old.
Exclusion Criteria
History of cytotoxic treatment
GNRH agonist treatment during or after chemotherapy
EF<50%
Positive history for BSO(bilateral salpingo-oophorectomy)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method AMH level before ,immediately after and 6 month after chemotherapy. Timepoint: Before chemotherapy , immediately after chemotherapy and 6 month after end of chemotherapy. Method of measurement: ELISA technique in central Imam Khomeini laboratory.
- Secondary Outcome Measures
Name Time Method