Effect of probiotic yoghurt on level of blood glucose in obese and overweight pregnant wome

Phase 2

Completed

Conditions: impaired blood glucose.
Abnormal glucose tolerance test

Registration Number: IRCT201604013706N31

Lead Sponsor: Research Deputy of Tabriz University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: Female

Target Recruitment: 130

Inclusion Criteria

20-22 weeks of pregnancy; FBS<92 mg/dl; BMI=25; age= 18 years; able to read and write
Exclusion criteria: multiple pregnancy; prior history of GDM; taking any medication likely to influence metabolism of glucose (in particular metformin, glucocorticoids or immunosuppressants); medical condition associated with altered glucose metabolism (in particular Cushing's syndrom/disease and hepatic cirrhosis); known major fetal abnormality; known regular ingestion of other probiotics; smoking; antibiotic intake during current pregnancy

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fasting blood glucose. Timepoint: Before the intervention, 4 weeks after intervention. Method of measurement: labratory assessment.;Blood glucose level 1 hour after intaking 75g oral glucose. Timepoint: 4 weeks after intervention. Method of measurement: labratory assessment.;Blood glucose level 2 hours after intaking 75g oral glucose. Timepoint: 4 weeks after intervention. Method of measurement: labratory assessment.

Secondary Outcome Measures

Name	Time	Method
Gestational diabetes. Timepoint: 4 weeks after intervention and after delivery. Method of measurement: Labratory Assessment.;Peeclampsia. Timepoint: 37th weeks of pregnancy and after delivery. Method of measurement: clinical (blood preassure) & labratory (proteinuria) assessment.;Preterm delivery. Timepoint: after delivery. Method of measurement: medical record assessment.;Birth weight. Timepoint: at birth, 10 days after birth. Method of measurement: medical record assessment, measurment of weight 10-12 days after birth by the researcher.;Macrosomia or Large for gestational age. Timepoint: after delivery. Method of measurement: based on birth weight.;Neonatal death. Timepoint: 30 days after birth. Method of measurement: asking from participant (woman) via calling.;Neonatal billirubine level. Timepoint: 3-5 days after delivery. Method of measurement: labratory assessment.