Comparing ventilation strategies for patients with de novo hypoxemic respiratory failure

Not Applicable

Completed

• Conditions: de novo hypoxemic respiratory failure; Respiratory; Respiratory failure, not elsewhere classified

• Registration Number: ISRCTN17904857
• Lead Sponsor: niversidad San Francisco de Quito

Brief Summary

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35966802/ (added 16/08/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2016-06-10
• Study Start: 2019-07-11
• Last Update Posted: 29 August 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

1. Age, 18 years or older.
2. Showed signs of acute respiratory failure in the emergency room (RR,> 25 breaths per minute, use of accessory muscles) for de novo hypoxemic respiratory failure (not produced by acute exacerbations of COPD, disease chronic pulmonary, or congestive heart failure), with PaO2 / FIO2 from mild to moderate according to the thresholds defined by the Berlin criteria for ARDS (9,10).

Exclusion Criteria

1. Facial deformity.
2.Obstruction in the upper airway by surgery or trauma.
3. Alterations in the central nervous system.
5. Hypercapnia encephalopathy.
6. Cardiogenic pulmonary edema, pneumothorax, pulmonary embolism thrombus, hemoptysis or shock septic.
7. Urgent intubation due to cardiorespiratory arrest and hemodynamic instability with systolic pressure less than 80 mmHg.
8. Demonstrated hemodynamic instability.
9. Demonstrated excess respiratory secretions.
10. Did not cooperate or were agitated.
11. Could not use the interface device.
12. Had recently undergone upper airway surgery.
13. Had received NIV with Do not resuscitate orders.

Study & Design

• Study Type: Observational
• Study Design: Not specified