ext generation sequencing of pathogens in neonates suspected for sepsis
Completed
- Conditions
- InfectionSepsis10019815
- Registration Number
- NL-OMON48675
- Lead Sponsor
- Maxima Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
- Clinical sepsis according to criteria according to Vermont Oxford Neonatal
Network:
Apnea, temperature instability, feeding intolerance, worsening respiratory
distress or hemodynamic instability.
- Blood culture obtained
- Gestational age above 26 weeks
- Birth weight above 800 gram
For the control group, neonates must be free of infection. Furthermore, a
clinical indication for a blood sample must be present. This group will be
matched with the cases for AD.
Exclusion Criteria
- Gestational age below 26 weeks
- Birth weight below 800 grams
- Antibiotic therapy within 72 hours before blood sampling
- Congenital abnormalities
- Genetic disorders
- Suspected syndromes
- Immunological disorders
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method