Study of the therapeutic role of plasmapheresis in patients with COVID-19 and its effect on serum levels of inflammatory factors

Bandare-abbas University of Medical Sciences0 个研究点目标入组 45 人开始时间: 待定最近更新: 2021年2月22日

试验速览

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•COVID-19 patients with positive Realtime PCR test for COVID-19
•tachypnea> Respiratory Rate 30 per minute and dyspnea, Oxygen saturation lower than 88% and fraction of inspired oxygen/ PaO2 ratio lower to equal 300, and increased lung involvement by more than 50% on CT scan.
•Patient with symptoms of respiratory failure, patient in need or under mechanical ventilation, patient with multiple organ failure and patient with shock symptoms
•Presence of two positive inflammatory markers including: Ferritin greater than 1000 or CRP above 50 mg/dl or ' ' +++ ' ' or Lactate dehydrogenase greater than 1000
•Lack of proper response to antiviral and corticosteroid therapy and hypoxia during hospitalization

•Low blood pressure lower than normal range, which causes a further decrease in blood pressure during plasmapheresis.
•Coagulation disorders that cause bleeding during plasmapheresis.
•Decreased blood platelets below the normal range, which may increase bleeding during plasmapheresis.

发起方

Bandare-abbas University of Medical Sciences