NCT06360601招募中1 期
The Effect of Intravenous Infusion of Labetalol Versus Hydralazine on Cerebral Hemodynamics of Preeclampsia Patients Prospective Randamized Study
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Cerebral blood flow
研究概览
简要总结
We study the effect of intravenous labetalol versus hydralazine in sever preeclampsia patients on cerebral blood flow and neurological outcome
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 25 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •patient with clinical diagnosis of sever preeclampsia
排除标准
- •Patient with history of previous intracranial lesion Patient with history of heart disease/allergy to drug Patient with history of arrhythmia/anticoagulation Any craniotemporal lesion
研究组 & 干预措施
Labetalol group
Active Comparator
干预措施: Labetalol Injection (Drug)
Hydralazine group
Active Comparator
干预措施: HydrALAZINE Injection (Drug)
结局指标
主要结局
Cerebral blood flow
时间窗: Pre intervention-after one hour of intervention
Mean cerebral blood flow and cerebral perfusion pressure
次要结局
未报告次要终点
研究者
Mai Kamal
Lecturer of anaesthesia
Tanta University
研究点 (1)
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