Gentamycin nebulisation to decrease infection in tracheostomy patients
Phase 3
Completed
- Conditions
- Health Condition 1: G978- Other intraoperative and postprocedural complications and disorders of nervous systemHealth Condition 2: G998- Other specified disorders of nervous system in diseases classified elsewhere
- Registration Number
- CTRI/2022/03/041202
- Lead Sponsor
- AIIMS Bhubaneswar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 70
Inclusion Criteria
Tracheostomised patients in the Neuro surgical ICU expected to survive to home discharge or 7 days post tracheostomy, whichever is greater
Exclusion Criteria
1 Creatinine clearance <30 ml per min
2 Vestibular instability/ hearing impairment.
3 Allergic to aminoglycosides.
4 Asthmatic patients.
5 H/o myasthenia gravis.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Compare the rates and change in the nature of pathogenic colonization of TT over the course of treatment from the ICU to home care: gentamicin group vs saline nebulization group.Timepoint: 48 hrs, 7, 30 and 60 days after tracheostomy
- Secondary Outcome Measures
Name Time Method complications and risk factors associated with drug resistant colisationTimepoint: 48 hrs, 7,30 and 60 days after tracheostomy