Multi-centre study of children with suspected bone and/or joint infection (BJI)

Not Applicable

• Conditions: Diagnosis of osteomyelitis (Bone/joint infection) in children aged 0-15 years; Musculoskeletal Diseases

• Registration Number: ISRCTN15471635
• Lead Sponsor: niversity of Oxford

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-04
• Last Update Posted: 22 July 2024
• Study Completion: 2025-09-30

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 7500

Inclusion Criteria

Current inclusion criteria as of 12/07/2024:

1. The child is aged between 0-15 years.
2. BJI is part of the differential diagnosis, even remotely, and even if the treating clinician believes BJI can be ruled out on the basis of the history and examination alone.
3. The duration of symptoms is less than 2 weeks at the time of attendance to acute healthcare.
4. Symptoms affecting the appendicular skeleton only.

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Previous inclusion criteria:

1. The child is aged between 0-15 years.
2. The treating clinician is suspicious of a diagnosis of bone and/or joint infection.
3. The duration of symptoms is less than 2 weeks at the time of attendance to acute healthcare.

Exclusion Criteria

Current exclusion criteria as of 12/07/2024:

1. There is evidence that the patient and/or parent/guardian would be unable to adhere to study procedures or complete follow-up, such as developmental delay or a developmental abnormality.
2. Limited comprehension by the parent guardian of the English language. This will be assessed by the recruiting team at participating sites.
3. Suspected infections affecting the axial skeleton (skull spine, or ribs).
4. Traumatic aetiology of symptoms

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Previous exclusion criteria:

1. There is evidence that the patient and/or parent/guardian would be unable to adhere to study procedures or complete follow-up, such as developmental delay or a developmental abnormality.
2. Limited comprehension by the parent guardian of the English language. This will be assessed by the recruiting team at participating sites.

Study & Design

• Study Type: Observational
• Study Design: Not specified