NL-OMON50075
Recruiting
Not Applicable
Study of the neuromuscular and multisystem features of patients with malignant hyperthermia or rhabdomyolysis related to a RYR1 variant - Multisystem features of malignant hyperthermia and rhabdomyolysis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Radboud Universitair Medisch Centrum
- Enrollment
- 60
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\* A history of malignant hyperthermia susceptibility (MHS), confirmed by
- •diagnostic RYR1 variant or IVCT related to a RYR1 variant and/or a history of
- •rhabdomyolysis related to a variant in RYR1
- •\* Minimum age 18 years old.
Exclusion Criteria
- •\* Patients diagnosed with a neuromuscular disease resulting in muscle weakness
- •(apart from RYR1 related rhabdomyolysis and malignant hyperthermia).
- •\* Patients with symptoms of angina pectoris.
- •\* Patients with contra\-indications for MRI\-scan are excluded.
- •Contra\-indications for MRI\-scan include metallic implants (vascular clips,
- •foreign bodies like metallic splinters in the eye, coronary and peripheral
- •artery stents, prosthetic heart valves, pacemakers and ICD\*s, cochlear
- •implants, breast tissue expanders and some other electronic implants or devices
- •and known claustrophobia.
- •\* Current malignancy
Outcomes
Primary Outcomes
Not specified
Similar Trials
Recruiting
Not Applicable
Multimodal neuromuscular information analysis of electroacupuncture for hemiplegia and shoulder pain in strokeHemiplegia Shoulder PainITMCTR2000002914Huazhong University of Science and Technology Shenzhen Union Hospital
Not yet recruiting
Not Applicable
Effect of restriction pressure on perceptual, metabolic and neuromuscular responsesAffectPhysical Exertion FatigueF01.470.047C23.888.369G11.427.683RBR-27xb3bniversidade Federal do Rio Grande do Norte
Completed
Not Applicable
Cognitive Impairment TrialNervous System Diseasescrebrovascular accident, Cognitive impairment, strokePACTR201807164763571self funded200
Completed
Not Applicable
EFFECT OF PROPRIOCEPTIVE NEUROMUSCULAR FACILITATION PATTERNS TO IMPROVE GAIT AND BALANCE IN ACUTE, SUB-ACUTE AND CHRONIC HEMIPLEGIC STROKE PATIENTSStroke of all of 3 stages acute subacute and chronic due to ischemia and hemorrhage.IRCT20210827052300N1The University of Faisalabad30
Not yet recruiting
Phase 2
Effect of diabetes on muscle strengthHealth Condition 1: E116- Type 2 diabetes mellitus with other specified complicationsCTRI/2021/07/035031Riyas Basheer K B