Anesthetic technique and oxidative stress during radical mastectomy.
Not Applicable
- Conditions
- Cancer
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 46
Inclusion Criteria
female patients
age older than 18 years.
who will be scheduled for modified radical mastectomy at the Mansoura University hospitals
Exclusion Criteria
Significant renal diseases.
Significant hepatic diseases.
Significant cardiovascular diseases
Suggestive history or signs of active inflammatory or infectious diseases.
Previous or bilateral breast surgery.
Breast reconstruction.
Previous chemotherapy.
Anemia and blood transfusion during the last 2 weeks.
Receiving vitamins and /or antioxidants (folic acid, omega, flavonoids, Vit A, B, C, D, E etc) during the last two months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the perioperative changes in plasma malondialdehyde (MDA) level
- Secondary Outcome Measures
Name Time Method changes in plasma level of glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD)