Effectiveness of Magnesium Sulphate for General Anesthesia in Adults
Phase 4
Recruiting
- Conditions
- Acute abdomen, Acute appendicitisR10.0
- Registration Number
- RBR-4xr92k
- Lead Sponsor
- Centro Universitário Tiradentes
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Patient diagnosed with acute appendicitis; Physical status ASA I and II; Age between 18 and 70 years.
Exclusion Criteria
Pregnancy; Neuromuscular disease; renal insufficiency; Body mass index greater than 30 km.m-2; Anticipation of difficulty in handling the airway; Chronic use of calcium channel blockers; Chronic use of medicines containing magnesium; Past allergy to magnesium sulfate.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical condition of tracheal intubation. It will be verified by means of laryngoscopy, positioning of the vocal cords and reactions that the patient presents at the moment of passage of the orotracheal tube in the airways. It will be evaluated using the intubation score system of the Good Clinical Research Practice guidelines. It will be classified as an acceptable and unacceptable clinical condition. Unacceptable clinical condition will occur if laryngoscopy is difficult, vocal cords are closed, or if there is muscle reaction at the time of passage of the tube through the vocal cords. Classification is by visual inspection.
- Secondary Outcome Measures
Name Time Method Heart rate, systemic blood pressure, adverse events and oxygen saturation. The heart rate will be verified by pulse oximetry and will be considered alteration when there is an increase or decrease of 10% of the initial value. Systemic blood pressure will be assessed using the sphygmomanometer. It is measured in mmHg and will be considered change when there is an increase or decrease of 10% of the initial value. The net research adverse events will be nausea, vomiting, hyperemia, arrhythmias and sweating. It will be collected through clinical observation. The arterial oxygen saturation will be collected by means of pulse oximetry and its value is shown in percentage number.