Drug - Food interaction of Oseltamivir(Tamiflu) in oral absorptio
- Conditions
- Influenza
- Registration Number
- JPRN-UMIN000003702
- Lead Sponsor
- Takuo Ogihara
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Male
- Target Recruitment
- 6
Not provided
the investigators must ensure that all subjects being considered to meet the following exclusion criteria or conditions: 1)history of allergy to Oseltamivir 2)difficult to take milk because of lactose intolerance etc. 3)disease thought to be decreased metabolic function of liver(acute hepatitis,chronic hepatitis,hepatic cirrhosis,liver carcinoma,jaundice) 4)decreased metabolic function of kidney 5)electrocardiogram (ECG) showing a QTc>460 msec 6)who take any drugs or supplement including St.John's wort within a week prior to test drug administration 7)fruit juice including grapefruit, orange or apple within 7 days prior to test drug administration 8)recent (past 3 months) participation in other clinical trial for investigational agent,the investigator determines this trial participation inadequate 9)donation of 400mL or more of blood within 3 months prior to participation, donation of 200mL or more of blood within 1 month prior to participation 10)any positive results of HBs-AG,HCV-AB,HIV AB,HIV AG,TPHA. 11)history of allergy to any medicines and foods 12)history of drug or alcohol abusement 13) the investigator determines inadequate
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method PK profiles of Oseltamivir and it's metabolite Ro64-0802 in plasma and urine
- Secondary Outcome Measures
Name Time Method