To assess the effect of transversus abdominis plane (TAP) block to control pain after removal of uterus.

Not yet recruiting

• Conditions: Inflammatory disease of uterus, unspecified,

• Registration Number: CTRI/2020/05/025379
• Lead Sponsor: Tata Motors Hospital

Brief Summary

Multimodal approach of analgesia (MMA) is the current standard practice to provide postoperative pain relief. TAP block has been used effectively as an adjunct to MMA. The results of various approaches of TAP block have given variable results and posterior TAP block is suppose to be more effective. However, more studies are required to prove its efficacy in various surgeries. We will evaluate the analgesic potential of posterior TAP block in abdominal hysterectomy. The primary outcome measure will be the amount of epidural morphine used in 24 hrs. The secondary out come measure would be the time for first request to analgesia, VAS scores and other side effects like PONV, sedation and respiratory depression. Assessment for patients satisfaction about analgesia will also be done. All the assessment will be done at 2,4,6,8,10,12 18 & 24 hrs. Sample size was calculated based on pilot study of morphine used and 64 patients (total) are required to get significant difference at 95% confidence level and 80% power for set p<0.05. Gpower software was used for sample size calculation. SPSS V22.0 will be used for statistical analysis. Depending upon the type of data, appropriate test will be used.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2020-05-26
• Study Start: 2020-05-29

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 64

Inclusion Criteria

• ASA grade I-III 2.
• Total abdominal hysterectomy done via lower abdominal transverse (Pfannenstiel) incision.

Exclusion Criteria

• Patient refusal.
• A history of drug allergy or local anaesthetic toxicity.
• Contraindications to regional anaesthesia (bleeding diathesis, infection at the site of block and peripheral neuropathy) 5.
• Change of anaesthetic technique to general anaesthesia.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Epidural morphine used	24hours

Secondary Outcome Measures

Name	Time	Method
Duration of analgesia,	difference in Vas scores,

Trial Locations

Locations (1)

Tata Motors Hospital; 🇮🇳 Singhbhum, JHARKHAND, India

Tata Motors Hospital

🇮🇳Singhbhum, JHARKHAND, India

Dr Ashok Jadon

Principal investigator

9234554341

jadona@rediffmail.com