The Randomized Controlled Trial for Evaluating the Efficacies of Tolvaptan in Patients with Chronic Kidney Disease
Not Applicable
- Conditions
- chronic kidney disease
- Registration Number
- JPRN-UMIN000014763
- Lead Sponsor
- Yokohama City University Medical Center Yokohama City University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
1)Patients undergoing hemodialysis or peritoneal dialysis during the study period 2)Previous history of tolvaptan use 3)The anuric patients 4)Patients without a sense of thirst 5)Patients without ability to intake water 6)Serum Na >=146mEq/L (within 3 days from a registration day) 7)Patients showing allergy to tolvaptan 8)Other cases which treating physicians regards as inappropriate
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method change of urine output
- Secondary Outcome Measures
Name Time Method 1) serum Cr 2) serum Na 3) body weight 4) symptoms of volume overload 5)the indispensability days untill a discharge