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tility of N acetyl cysteine in preventing progression of Covid19 pneumonia.

Not Applicable
Conditions
Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
Registration Number
CTRI/2021/11/038136
Lead Sponsor
Rajiv Gandhi University of Health Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.Hospitalized adult age 18 to 70 years

2.Laboratory-confirmed SARS-CoV-2 infection as determined by polymerase chain reaction (PCR) or other commercial or public health assay

3.Moderate Covid-19 patients not requiring organ support

4.Mild Covid requiring hospitalization

5 Duration of Hospital less than 48 hours.

Exclusion Criteria

1. Unlikely to survive after 48 hours from screening or unlikely to remain at the investigational site beyond 48 hours

2. Requiring organ support at screening (Organ support defined as need for ICU care, mechanical ventilation, Non Invasive Ventilation (NIV), High flow Nasal Oxygen at screening

3. Participation in any other clinical trial of an experimental treatment for COVID-19

4. Known hypersensitivity to the trial drug or its components

5. Pregnant women or women who are breastfeeding

6. Consideration by the investigator, for any reason, that the subject is an unsuitable candidate to receive study treatment

7. Unable to provide consent

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1.Need for Organ Support <br/ ><br>2.All-cause Mortality at 28 days <br/ ><br> <br/ ><br>Timepoint: 1.All-cause Mortality at 28 days <br/ ><br> <br/ ><br>
Secondary Outcome Measures
NameTimeMethod
1. Change in RNA Levels(CT Values) <br/ ><br>2. Change in cytokines and biomarker levelsTimepoint: day 1, 3 and 5
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