Changes in Cerebrovascular Reactivity During Cognitive Activation After Cardiopulmonary Bypass: Relation With Intraoperative Embolic Load and Postoperative Neuropsychological Dysfunctions
Not Applicable
Completed
- Conditions
- CABG-Patients
- Registration Number
- NCT00394108
- Lead Sponsor
- University Ghent
- Brief Summary
The study aims to evaluate neuropsychological disorders in CABG patients. Measurements are performed 1 day before, 6 days, 6 months and 3-5 years after the surgery. The relation with cerebrovascular reactivity and embolic load (measured by transcranial Doppler Ultrasonography) is evaluated. Two surgery techniques (on- and off-pump CABG) are compared.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 66
Inclusion Criteria
- CABG-patients (not urgent)
- < 70 years old
- Righthanded
Exclusion Criteria
- Neurological or psychiatric disease
- Psychoactive medication
- Valve operation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Neuropsychological status after 6 days, 6 months and 3-5 years
- Secondary Outcome Measures
Name Time Method Relation with intra-operative embolic load
Trial Locations
- Locations (1)
University Hospital Ghent
🇧🇪Ghent, Belgium