The effect of EMDR therapy in patients with bipolar disorder and a history of traumatic events: a randomized controlled trial.

Conditions: bipolar disorder
manic depressive illness
10026753

Registration Number: NL-OMON46084

Lead Sponsor: Altrecht GGZ (Den Dolder)

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 36

Inclusion Criteria

- * 18 years of age
- A primary diagnosis of DSM-5 bipolar I or II disorder
- A history of (a) traumatic event(s) that is still causing clinically relevant distress

Exclusion Criteria

- Organic brain disorder
- Mental retardation
- Dependency of drugs and/or alcohol
- Severe suicidality or psychosis in the last month
- Moderate to severe depressive or hypomanic symptoms at the start of the intervention (CGI-BP mania > 4, CGI-BP depression > 5).
- Patients are currently in some other form of psychological treatment for trauma

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter is a significant decrease in affective symptoms<br /><br>measured by daily mood reports with the National Institute of Mental Health<br /><br>Life Chart Methodology (NIMH LCM), Altman Selfrating Mania Scale-NL (ASRM-NL)<br /><br>and/or the Inventory of Depressive Symptoms-Self Report (IDS-SR). </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary study parameter is a significant reduction of trauma symptoms<br /><br>measured by the Clinician Administered PTSD Scale (CAPS) and the PTSD Checklist<br /><br>for Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 (PCL-5).<br /><br><br /><br>Another study parameter is that EMDR does not lead to mood episodes or an<br /><br>increase of mood symptoms. </p><br>