Neurobehavioral Correlates of Craniosynostosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 535
- 试验地点
- 4
- 主要终点
- Neurodevelopment as assessed by the Bayley Scales of Infant Development II
研究概览
简要总结
To learn more about the cognitive and motor development of infants and young children born with a craniofacial defect called craniosynostosis.
详细描述
In the first phase of this multi-site, 10-year longitudinal study, infants with one of four types of single-suture craniosynostosis were recruited: sagittal, metopic, right unilateral coronal, and left unilateral coronal. A case-matched "control" group of healthy, normal infants was also followed. This study, which is now in its second phase, is following this same cohort of children at the age of 7 years.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 2 Months 至 7 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Neurodevelopment as assessed by the Bayley Scales of Infant Development II
时间窗: 1st assessment - post diagnosis, pre surgery. 2nd assessment - Target age 18 months. 3rd assessment - Target age 36 months.
次要结局
- Neurodevelopment as assessed by the Wechsler Intelligence Scale for Children Version IV(Target age 7 years)
研究者
Matt Speltz
Principal Investigator
Seattle Children's Hospital