Studies Aiming at Identifying Predictors for Fertility Treatments' Outcomes and to Evaluate the Efficacy and Safety of Fertility Preservation
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 50,000
- 试验地点
- 1
- 主要终点
- Efficacy and safety of fertility preservation - Long-term follow-up
研究概览
简要总结
This study analyses clinical data prospectively collected for over a decade in several clinical databases. Electronic medical records are available since 1998.
Since 2011 the subgroup of patients that undergo fertility preservation are invited to participate in a prospective study aiming at long-term follow-up after fertility preservation for oncologic and non-oncologic conditions.
详细描述
In this study, the investigators aim at analyze the treatment outcomes of patients with infertility, their clinical characteristics and biochemical parameters aiming at identifying predictors for the treatment outcomes.
For the cohort of patients that have undergone fertility preservation at Karolinska University Hospital, the investigators aim at investigating efficacy and safety of the procedures.
The data can be expanded by using additional databases such as the Regional Cancer Registry and other registries.
Analysis of data collected will allow the investigation of efficacy and safety of fertility preservation, identification of predictors for fertility outcomes,prediction of future activities and costs of the procedures.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- — 至 56 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •infertile patients and patients who undergo fertility preservation
排除标准
- •Healthy individuals, fertile population
结局指标
主要结局
Efficacy and safety of fertility preservation - Long-term follow-up
时间窗: 2028
Correlation between method of fertility preservation and pregnacy rate
次要结局
- Efficacy and safety of COS using GnRHa for fertility preservation in BC patients(Observed outcomes in patients registered between 1995 and 2017. Follow up until end of 2018.)
- Clinical outcome of fertility treatments i breast cancer patients(5-7 years post diagnosis)
- Predictors of effictive fertility treatment(patient data collected from time of treatment, pregnancy rate until end of study)
研究者
Kenny Rodriguez-Wallberg
MD, PhD, Associate Professor
Karolinska Institutet