A Comparative Evaluation of Advanced PRF (A-PRF) And Titanium PRF (T-PRF) in Maxillary Sinus Augmentation Through Crestal Approach in Implant Placement - An In Vivo Study
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- The outcome of the study will help in comparing the formation of bone density using TPRF and APRF in maxillary sinus augmentation
研究概览
简要总结
The present Thesis “A Comparative Evaluation of Advanced – PRF (A-PRF) And Titanium – PRF (T-PRF) in Maxillary Sinus Augmentation Through Crestal Approach in Implant Placement - An In Vivo Study†compared the regenerative potential of different preparations of platelet concentrate to access the effect of platelet rich plasma on dental implants specifically and on maxillary sinus elevation. It was held over a period of 2 years. The study was carried out on patients having ridge resorption and requiring rehabilitation involving maxillary sinus lift in the out-patients department of Prosthodontics Crown & Bridge and Implantology in Sardar Post Graduate Institute of Dental and Medical Sciences.
In this present study implants were placed using Osseodensification Densah Drills for sinus augmentation followed by bone grafting. The objective of the present study was to compare the regenerative potential of different types of platelet concentrate Advanced - PRF (A-PRF) and Titanium – PRF (T-PRF) on indirect maxillary sinus elevation using crestal approach.
Bone augmentation techniques have increasingly been indicated for re-creating adequate bone height and volume suitable for dental implant sites. This is particularly applicable in the severely atrophic posterior maxilla where sinus perforation is a very common complication and sinus floor elevation or lift is frequently considered a standard procedure.
In this study different types of platelet concentrates Advanced - PRF (A-PRF) and Titanium – PRF (T-PRF) were centrifuged at different speeds for different times to be used for bone augmentation and maxillary sinus lift.
An outcome of these platelet concentrates for bone defect and maxillary lift was evaluated after the placement of these concentrates for a period of 6 month follow up.
A CBCT was evaluated pre and post administration of these concentrates to check the bone augmentation and maxillary sinus floor changes after 6 months with evaluation of implant stability using Ostell density via CBCT.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients willing for voluntary participation & have signed informed consent for the described procedure Patients having good physical and mental health and well formed or moderately formed residual alveolar ridge Systemically healthy subjects Patients requiring Sinus augmentation prior to placement of implant Patients well motivated for implant therapy and maintaining good oral hygiene Patients requiring bilateral sinus lift Bone height between 4 to 6 mm.
排除标准
- •Immunocompromised patients Grafted site previous or during implant placement Patients of chronic and aggressive periodontitis Flapless procedures Alcohol or drug abuse Psychologically compromised patients Patients with temporomandibular disorders severe residual ridge resorption orofacial tumors and gross facial deformity mucositis radiation therapy parafunctional habit Patients with active diseases of the implant bed example residual cysts Cancer Patients ongoing chemotherapy Patients on steroid therapy Severe Metabolic Diseases Immunocompromised patients Abnormal Platelet Function Bisphosphonates Therapy.
结局指标
主要结局
The outcome of the study will help in comparing the formation of bone density using TPRF and APRF in maxillary sinus augmentation
时间窗: 6 months
次要结局
- Thicker bone density and good postoperative healing(6 months)
研究者
Kratika Rastogi
Sardar Post Graduate Institute of Dental and Medical Sciences