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A Study to Explore Prognoses of the Patients With N2 Non-small Cell Lung Cancer

Completed
Conditions
Non-small Cell Lung Cancer
Interventions
Procedure: Surgeries
Registration Number
NCT03451526
Lead Sponsor
Tang-Du Hospital
Brief Summary

The trial was designed to compare the effectiveness of radical resections of lung cancer plus adjuvant chemotherapies and perioperative chemotherapies in the patients with N2 non-small cell lung cancer

Detailed Description

The trial is a multi-centre real-world non-interventional observational study. The Chinese patients with N2 non-small cell lung cancer enrolled from 2014 to 2017 who received radical resections of lung cancer and adjuvant chemotherapies will be included in the study and the study data on patient demographic/tumor biological characteristics and clinical treatment will be collected to evaluate compare effectiveness of radical resection of lung cancer plus adjuvant chemotherapies and perioperative chemotherapies after surgeries.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
2929
Inclusion Criteria
  • Patients with radical resection of lung cancer enrolled from 2014 to 2019;
  • Pathologically diagnosed patients with non-small cell lung cancer;
  • Patients with age > 18 years old;
  • Patients who did not receive chest surgeries before hospitalization;
  • Patients with N2 lymph nodes (+) after surgeries;
  • Patients who received lymphadenectomy for one group or more groups of lymph nodes;
Exclusion Criteria
  • Patients with second primary tumors or multiple primary tumors;

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Surgeries+adjuvant chemotherapiesSurgeriesPatients who received radical resection of lung cancer + adjuvant chemotherapies
Perioperative chemotherapiesSurgeriesPatients who received perioperative chemotherapies
Primary Outcome Measures
NameTimeMethod
Overall survival2014 - 2017

Overall survival

Secondary Outcome Measures
NameTimeMethod
Disease-free survival2014 - 2017

Disease-free survival

Trial Locations

Locations (10)

Jiangsu cancer hospital

🇨🇳

Nanjing, Jiangsu, China

Huaxi Hospital Affiliated to Sichuan University

🇨🇳

Chengdu, Sichuan, China

China PLA General Hospital

🇨🇳

Beijing, Beijing, China

Tongji Hospital Affiliated to Huazhong Technology Hospital

🇨🇳

Wuhan, Hubei, China

Shanghai Chest Hospital

🇨🇳

Shanghai, Shanghai, China

Henan cancer hospital

🇨🇳

Zhengzhou, Henan, China

China-Japan Friendship Hospital

🇨🇳

Beijing, Beijing, China

First Hospital Affiliated to Zhejiang University

🇨🇳

Hangzhou, Zhejiang, China

Tianjin Chest Hospital

🇨🇳

Tianjin, Tianjin, China

Xi'an Tangdu Hospital

🇨🇳

Xi'an, Shaanxi, China

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