跳至主要内容
临床试验/NCT07552571
NCT07552571招募中不适用

Evolution and Driving Mechanism of Proactive Health Behavior in Chronic Disease Patients Based on Goal Commitment

Xiong Juyang1 个研究点 分布在 1 个国家目标入组 600 人开始时间: 2025年5月15日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
600
试验地点
1
主要终点
Change in Proactive Health Behavior Score

研究概览

简要总结

Chronic diseases such as hypertension, diabetes, and dyslipidemia are major contributors to mortality and healthcare burden worldwide. Despite high awareness of health risks, many patients fail to adopt proactive health behaviors due to behavioral inertia and a gap between knowledge and action.

This study aims to investigate the evolution and driving mechanisms of proactive health behavior in patients with chronic diseases based on goal commitment theory. By integrating prospect theory and evolutionary game theory, this study will explore how behavioral strategies evolve under different levels of goal commitment.

In addition, a behavioral intervention based on the Stimulus-Organism-Response (SOR) model will be developed to enhance patient activation and promote adherence to proactive health behaviors. A parallel controlled intervention study will be conducted to evaluate the effectiveness of the goal commitment-based intervention.

The findings of this study are expected to provide theoretical and practical evidence to improve chronic disease management and promote proactive health behaviors.

详细描述

Chronic diseases, including hypertension, diabetes, and dyslipidemia, account for a substantial proportion of morbidity, mortality, and healthcare expenditure. Although a large proportion of patients are aware of their health risks, more than half fail to adopt proactive health behaviors. This gap between awareness and action is often attributed to behavioral inertia and insufficient motivation.

This study aims to explore the evolution and driving mechanisms of proactive health behavior among patients with chronic diseases based on goal commitment theory. The theoretical framework integrates prospect theory and evolutionary game theory to model behavioral decision-making under uncertainty and dynamic interactions.

First, a theoretical model will be constructed to simulate the evolution of proactive health behaviors under different levels of goal commitment, using evolutionary game analysis. Second, a conceptual framework based on the Stimulus-Organism-Response (SOR) model will be developed to examine how goal commitment influences patient activation and social norms, thereby affecting proactive health behavior.

Empirical data will be collected through multi-site surveys among patients with chronic diseases. Subsequently, a parallel controlled intervention study will be conducted to evaluate the effectiveness of a goal commitment-based intervention in improving proactive health behaviors.

Inclusion criteria include adult residents diagnosed with at least one chronic condition (hypertension, diabetes, or dyslipidemia), with adequate cognitive ability and willingness to participate. Exclusion criteria include inability to participate in group activities, current hospitalization, or severe psychiatric or cognitive disorders.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Health Services Research
盲法
None

入排标准

年龄范围
45 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Residents living in the study area for at least 1.5 years
  • Diagnosed with at least one chronic disease, including hypertension, diabetes mellitus, or dyslipidemia
  • Conscious and able to communicate effectively
  • Educational level of primary school or above
  • Able to use a smartphone and common mobile applications (e.g., WeChat)
  • Willing to participate and provide written informed consent

排除标准

  • Non-residents of the study area
  • Unable to participate in group-based intervention activities
  • Currently hospitalized
  • Diagnosed with severe cognitive impairment, dementia, or psychiatric disorders
  • Participants with severe comorbidities that may interfere with study participation

研究组 & 干预措施

Goal Commitment Intervention Group

Experimental

Participants in this group will receive a goal commitment-based behavioral intervention designed to enhance proactive health behaviors. The intervention includes structured goal-setting, behavioral activation strategies, and continuous support to improve adherence to chronic disease management.

干预措施: Goal Commitment-Based Behavioral Intervention (Behavioral)

Usual Care Control Group

Active Comparator

Participants in this group will receive routine chronic disease management or standard health education without additional behavioral intervention.

干预措施: Usual Care (Other)

结局指标

主要结局

Change in Proactive Health Behavior Score

时间窗: Baseline to 6 months after intervention

The primary outcome is the difference in the mean change of proactive health behavior scores between the intervention group and the control group at 6 months after the intervention. Proactive health behaviors will be assessed using a validated Proactive Health Behavior Scale, including overall score and component scores.

次要结局

  • Change in Metabolic Syndrome (MetS) Score(Baseline to 6 months after intervention)
  • Change in Proactive Health Behavior Score at 3 Months(Baseline to 3 months after intervention)
  • Change in Fasting Blood Glucose (FBG) at 3 Months(Baseline to 3 months after intervention)
  • Change in Fasting Blood Glucose (FBG)(Baseline, 3 months, and 6 months after intervention)
  • Change in Triglycerides (TG)(Baseline, 3 months after intervention, and 6 months after intervention)
  • Change in High-Density Lipoprotein Cholesterol (HDL-C)(Baseline, 3 months after intervention, and 6 months after intervention)
  • Change in Blood Pressure(Baseline, 3 months after intervention, and 6 months after intervention)
  • Change in Body Mass Index (BMI) at 3 Months(Baseline to 3 months after intervention)
  • Change in Triglycerides (TG) at 3 Months(Baseline to 3 months after intervention)
  • Change in High-Density Lipoprotein Cholesterol (HDL-C) at 3 Months(Baseline to 3 months after intervention)
  • Change in Systolic Blood Pressure (SBP) at 3 Months(Baseline to 3 months after intervention)
  • Change in Diastolic Blood Pressure (DBP) at 3 Months(Baseline to 3 months after intervention)

研究者

发起方
Xiong Juyang
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Xiong Juyang

Principal Investigator

Huazhong University of Science and Technology

研究点 (1)

Loading locations...

相似试验