To compare effectiveness of dexmeditomidine versus nalbuphine for pain relief in spinal anaesthesia after lower limb surgeries
Phase 2
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/08/056624
- Lead Sponsor
- Sri Guru Ram Das Institute of Medical Sciences and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients who are consenting for the study
2. Patients undergoing lower limb surgeries
3. American Society of Anesthesiology (ASA) Grade I and II
Exclusion Criteria
1. Contraindications to regional anaesthesia such as anatomic disorders of spine, shock, coagulation and bleeding disorders, local site infections.
2. Patients with hypersensitivity to study drugs
3. Pregnant female
4. Patients with the history of neuropsychiatric problems
5. Patients with communication problems that will not able to understand visual analogue scale (VAS).
6.Patients refusing for consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Post-operative analgesia with dexmedetomidine & nalbuphine <br/ ><br>as adjuvants combined with 0.5 percent hyperbaric levobupivacaine in spinal anesthesia.Timepoint: till 24 hours
- Secondary Outcome Measures
Name Time Method To evaluate dexmedetomidine & nalbuphine in terms of onset, duration of sensory and motor block, postoperative analgesic effect, sedation score, side effects of study drugsTimepoint: till 24 hours