The incidence, prevalence and genotype of genital Human Papillomavirus infections in females before and after renal transplantation.

Completed

• Conditions: Genital HPV infection; HPV infection of the cervix and vulva; 10016417

• Registration Number: NL-OMON37921
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

- Female sex;
- Age >= 18 years at start of the study;
- Eligible for renal transplantation;
- Operation at the Radboud University Nijmegen Medical Centre

Exclusion Criteria

- Patient not willing to sign and/or return the informed consent form;
- Patient refusing additional treatment in case of abnormal findings at the first visit;
- Patient being pregnant, or within a period of 3 months after delivery;
- Patient being within a period of 3 months after miscarriage.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter is the prevalence of hr-HPV infections before and<br /><br>after renal transplantation.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints are the incidence of HPV infections before and after renal<br /><br>transplantation and the genotype of the HPV infections per time point, and the<br /><br>findings of gynaecological examination before transplantation in relation with<br /><br>the hrHPV status, viral load of a hrHPV infection in time, quality of life<br /><br>before and after transplantation and the correlation of the quality of life<br /><br>with the incidence/prevalence of genital HPV infection/genital (pre)malignant<br /><br>lesions</p><br>