Prediction of Chronic Kidney Disease Following Pre-eclampsia: Diagnosis and Early Care

Not Applicable

Recruiting

• Conditions: Preeclampsia

• Registration Number: NCT05056701
• Lead Sponsor: Centre Hospitalier le Mans

Brief Summary

Pre-eclampsia (PE) is a pregnancy-associated syndrome of variable severity, classically defined by the combination of hypertension and proteinuria in a previously non-hypertensive or proteinuric patient. These symptoms normally resolve within 2-3 months after delivery regardless of the severity of the pre-eclampsia.

Regardless of its definition, preeclampsia is associated with an increased risk of obstetric events and, for the mother, an increased risk of developing chronic kidney disease (CKD), hypertension, diabetes and cardiovascular disease in the broad sense.

The relationship between preeclampsia and Chronic Kidney Disease is, however, complex and not fully understood.

Investigator proposes an interventional study to identify the diagnosis of Chronic Kidney Disease in patients who have developed an episode of Preeclampsia.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-05
• Status Verified: 2021-09
• Study First Submitted: 2021-09-16
• Study First Submitted QC: 2021-09-16
• Study First Posted: 2021-09-24
• Last Update Submitted: 2021-09-28
• Last Update Posted: 2021-10-05
• Primary Completion: 2036-08-05
• Study Completion: 2036-08-05

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 400

Inclusion Criteria

• Meeting the preeclampsia criteria according to the ISSHP 2018 definitions
• Having signed the informed consent

Exclusion Criteria

• Patient with mental disability or language barrier preventing understanding of the study or consent
• Person deprived of liberty by judicial or administrative decision
• Person under forced psychiatric care
• Person subject to a legal protection measure

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
prevalence of the Chronic Kidney Disease (CKD)	until 10 years	prevalence of the CKD is measured by the the rate of new CKD Diagnoses (according to the standard definitions)