Investigation of Semaphorin 4D Levels in gingival crevicular fluid of healthy gums and in pyorrhea and itâ??s response to teeth cleaning treatment .
Not Applicable
Completed
- Conditions
- Health Condition 1: K053- Chronic periodontitis
- Registration Number
- CTRI/2020/12/029934
- Lead Sponsor
- TPCTs Terna dental college and hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 75
Inclusion Criteria
1.Subjects between the age group of 30 â?? 60 years.
2.Subjects who have not received periodontal therapy, within
preceding six months.
3.Subjects who readily give informed consent for the study.
4.Systemically healthy patients .
Exclusion Criteria
1.Consumption of tobacco in any form and alcoholics.
2.Pregnant and lactating females.
3. Subjects who have received anti-inflammatory, antibiotic and
steroid drugs in previous three months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To determine the level of GCF SEMA4D in <br/ ><br>periodontally healthy patients. <br/ ><br>2.To determine the level of GCF SEMA4D in <br/ ><br>chronic periodontitis patients. <br/ ><br>3.To compare the levels of GCF SEMA4D in <br/ ><br>periodontally healthy and chronic periodontitis <br/ ><br>patients. <br/ ><br>4.To correlate the effect of scaling and root <br/ ><br>planing on the level of GCF SEMA4D in <br/ ><br>patients with chronic periodontitis. <br/ ><br>Timepoint: Baseline <br/ ><br>4 weeks after scaling and root planing
- Secondary Outcome Measures
Name Time Method To evaluate improvement in plaque index <br/ ><br>,gingival index,pocket probing depth and clinical <br/ ><br>attachment level in patients with chronic <br/ ><br>periodontitis 4 weeks after scaling and root <br/ ><br>planing .Timepoint: plaque index ,gingival index,pocket probing <br/ ><br>depth and clinical attachment level in patients <br/ ><br>with chronic periodontitis will be taken at <br/ ><br>baseline and then 4 weeks after scaling and root <br/ ><br>planing .