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Vaccinex

Vaccinex logo
🇺🇸United States
Ownership
Public, Subsidiary
Established
1997-01-01
Employees
40
Market Cap
$9M
Website
http://www.vaccinex.com
Introduction

Vaccinex, Inc. operates as a clinical-stage biotechnology company. It engages in the development of targeted bio therapeutics to treat serious diseases and conditions with unmet medical needs, including cancer, neurodegenerative diseases, and autoimmune disorders. The firm focuses on the development of Pepinemab for the treatment of non-small cell lung cancer, or NSCLC, osteosarcoma, melanoma, and Huntington’s disease. Its product pipeline includes the SEMA4D antibody platform and ActivMAb antibody discovery platform. The company was founded by Maurice Zauderer in April 2001 and is headquartered in Rochester, NY.

Clinical Trials

7

Active:1
Completed:6

Trial Phases

2 Phases

Phase 1:6
Phase 2:1

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (7 trials with phase data)• Click on a phase to view related trials

Phase 1
6 (85.7%)
Phase 2
1 (14.3%)

Trial of Immunotherapy With Avelumab and Pepinemab As Second Line For Patients With Metastatic Pancreatic Adenocarcinoma

Phase 1
Active, not recruiting
Conditions
Metastatic Pancreatic Adenocarcinoma
Interventions
First Posted Date
2021-11-01
Last Posted Date
2025-05-21
Lead Sponsor
Vaccinex Inc.
Target Recruit Count
48
Registration Number
NCT05102721
Locations
🇺🇸

University of Rochester Medical Center, Rochester, New York, United States

Pepinemab in Combination With Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Phase 1
Completed
Conditions
Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (HNSCC)
Interventions
First Posted Date
2021-03-25
Last Posted Date
2025-01-08
Lead Sponsor
Vaccinex Inc.
Target Recruit Count
49
Registration Number
NCT04815720
Locations
🇺🇸

Highlands Oncology Group, PA - North Hills, Springdale, Arkansas, United States

🇺🇸

California Cancer Associates for Research and Excellence (CCARE)-Fresno, Fresno, California, United States

🇺🇸

UCSF Medical Center at Mission Bay, San Francisco, California, United States

and more 12 locations

SEMA4D Blockade Safety and Brain Metabolic Activity in Alzheimer's Disease (AD)

Phase 1
Completed
Conditions
Alzheimer Disease
Interventions
Drug: Placebo
First Posted Date
2020-05-08
Last Posted Date
2024-08-22
Lead Sponsor
Vaccinex Inc.
Target Recruit Count
50
Registration Number
NCT04381468
Locations
🇺🇸

Pacific Research Network, Inc, San Diego, California, United States

🇺🇸

Georgetown University, Washington, District of Columbia, United States

🇺🇸

Brain Matters Research, Stuart, Florida, United States

and more 10 locations

VX15/2503 in Combination With Avelumab in Advanced Non-small Cell Lung Cancer

Phase 1
Completed
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
First Posted Date
2017-08-31
Last Posted Date
2022-05-02
Lead Sponsor
Vaccinex Inc.
Target Recruit Count
62
Registration Number
NCT03268057
Locations
🇺🇸

Highlands Oncology Group, PA, Fayetteville, Arkansas, United States

🇺🇸

University of California Los Angeles (UCLA), Los Angeles, California, United States

🇺🇸

Mayo Clinic, Rochester, Minnesota, United States

and more 7 locations

A Study in Subjects With Late Prodromal & Early Manifest HD to Assess the Safety, Tolerability, pk, and Efficacy of Pepi

Phase 2
Completed
Conditions
Huntington's Disease
Interventions
Drug: Placebo
First Posted Date
2015-06-25
Last Posted Date
2022-05-02
Lead Sponsor
Vaccinex Inc.
Target Recruit Count
301
Registration Number
NCT02481674
Locations
🇺🇸

University of Alabama at Birmingham, Birmingham, Alabama, United States

🇺🇸

University of California, San Diego, La Jolla, California, United States

🇺🇸

University of California San Francisco, San Francisco, California, United States

and more 28 locations
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