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Observation on the effect of transcutaneous electrical acupoint stimulation nursing on prevention of bone marrow suppression in patients with oral and maxillofacial tumors after chemotherapy

Phase 1
Conditions
Oral and Maxillofacial Tumors
Registration Number
ITMCTR2000003581
Lead Sponsor
Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1. Patients who were diagnosed as oral and maxillofacial tumors by pathology or cytology from January 1, 2021 to December 31, 2021;
2. Aged 18 to 80 years old, with basic cognitive ability;
3. Karnofsky (KPS) functional status score >=60 points, expected to survive for more than 3 months;
4. Those who have no severe heart, liver, brain, kidney and other organic damage and bone marrow hematopoietic dysfunction;
5. Check blood routine before chemotherapy, and evaluate patients whose bone marrow suppression score is 0 according to WHO's grading standard for side effects of chemotherapy;
6. The chemotherapy regimen is limited to the initial chemotherapy and the TPF regimen (docetaxel + cisplatin + 5-Fu) patients will not receive other chemotherapy drugs or concurrent radiotherapy during chemotherapy;
7. Sign the informed consent and get the approval of the ethics committee.

Exclusion Criteria

1. Complicated with hematological tumor;
2. People with mental illness;
3. Pregnant women;
4. Patients with myelosuppression before chemotherapy;
5. Patients with implanted on-demand pacemakers.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Myelosuppression grade;White blood cell count;Neutrophil count;Red blood cell count;Anti-myelosuppressive medication;Platelet count;
Secondary Outcome Measures
NameTimeMethod
Quality of Life;cancer related fatigue;TCM body constitution;Comfort;
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