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A research study done to assess the effect of a drug called ketamine on brain function outcome in patients suffering from severe traumatic head injury

Phase 4
Completed
Conditions
Health Condition 1: S062- Diffuse traumatic brain injury
Registration Number
CTRI/2018/09/015729
Lead Sponsor
All India Institute of Medical Sciences New Delhi
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
60
Inclusion Criteria

ASA (American Society of Anesthesiologist) grade I and II patients

Severe traumatic brain injury

Mechanically ventilated

Intracranial pressure monitoring being done

Exclusion Criteria

Age (less than 18 years and greater than 49 years)

glaucoma

Life threatening multiple injuries

Severe systemic disease ASA grade more than III

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
eurological outcome as assessed by Glasgow Outcome Scale <br/ ><br>Timepoint: 3 months <br/ ><br>
Secondary Outcome Measures
NameTimeMethod
Effect on Intracranial pressure, cerebral perfusion pressure and mean arterial pressureTimepoint: 1 hour
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