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Investigation of the gut as a possible reservoir for the JC Polyoma virus in patients with multiple sclerosis under treatment with natalizumab

Recruiting
Conditions
A81.2
Progressive multifocal leukoencephalopathy
Registration Number
DRKS00017542
Lead Sponsor
Biogen, Inc
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
40
Inclusion Criteria

multiple sclerosis patients under treatment with natalizumab, signed form of consent

Exclusion Criteria

consent denied

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Identification of the JCPyVirus in stool, blood and urine samples during treatment with natalizumab. When patients arrive in the clinic to receive their treatement, blood and urine samples will be obtained right away. In the days following the infusion a stool sample will be sent to the clinic by the patient.
Secondary Outcome Measures
NameTimeMethod
Quantitative and qualitative analysis of the Virus DNA in the stool, blood and urine samples.
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