Anaerobic threshold in patients with pectus excavatum

Withdrawn

• Conditions: funnel chest; pectus excavatum; 10082206; 10013369

• Registration Number: NL-OMON42298
• Lead Sponsor: Atrium Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 27

Inclusion Criteria

- Age between 18 to 40 years
- Planned for reconstruction of the chest wall with Nuss Procedure
- Haller index >2,5
- Symptoms related to exercise

Exclusion Criteria

- Severe lung disease
- Preexisting heart disease
- Not able to do a cycle exercise test
Absolute contra-indications for exercise test:
- Acute myocardial infarction
- Unstable angina
- Syncope
- Active endocarditis
- Acute myocarditis
- Symptomatic severe aortic stenosis
- Uncontrolled heart failure
- Acute pulmonary embolus or infartction
- Thrombosis of lower extremities
- Suspected aortic dissection
- Uncontrolled astma
- Pulmonary edema
- Saturation in rest * 85%
- Respiratory failure
- Acute nonpulmonary disorder that may affect exercise performance
- Non-cooperative patient

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- The anaerobic threshold is shown as percentage of the predicted VO2max.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- VO2max<br /><br>- Heart ratemax<br /><br>- Subjective exercise intolerance<br /><br>- Cosmetic / psychological problems<br /><br>- Borg scale (for both respiratory load as well as the fatigue in the legs)<br /><br>- Short Form 36 questionnaire</p><br>