IMSI versus ICSI in patients with severe male factor infertility and repeated ICSI failure

Not Applicable

Recruiting

• Conditions: Fertility-male; Fertility-female; Infertility with repeated ICSI failure

• Registration Number: PACTR201411000928146
• Lead Sponsor: Obestetrics and Gynaecology Department, Faculty of Medicine, University of Alexandria

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-11-06
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 140

Inclusion Criteria

Primary or secondary infertility
Having good ovarian reserve(AMH>1.5,AFC >5 and basal FSH< 10mIu/L )
All underwent the long luteal gonadotrophin agonist proto-
Col for ovarian stimulation.
All with at least one previous failed ICSI
Male partner with sever oligospermia sperm conc < 5(106
Per ml) and sever teratospermia normal form <4%.

Exclusion Criteria

Endocrine disorders
Associated other medical conditions (hypertention, diabetes)
Abnormal uterine factor diagnosed by vaginal sonogrphy, Hysteroscopy, Hysterosalpingography or previous uterine surgery.
Stage IV endometriosis or previous ovarian surgery.
Male partners with TESE (testicular epididimal sperm extraction)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
umber of embryos;Fertilization rate;Embryo grading.;Implantation rate .

Secondary Outcome Measures

Name	Time	Method
Pregnancy rate