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Clinical Trials/ACTRN12618000496213
ACTRN12618000496213
Completed
未知

Is dysfunction of brain blood vessels associated with cognitive impairment in type-1 diabetes?

niversity of Newcastle0 sites40 target enrollmentApril 5, 2018
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ConditionsType 1 Diabetes MellitusMetabolic and Endocrine - DiabetesMental Health - Studies of normal psychology, cognitive function and behaviour

Overview

Phase
未知
Intervention
Not specified
Conditions
Type 1 Diabetes Mellitus
Sponsor
niversity of Newcastle
Enrollment
40
Status
Completed
Last Updated
6 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
April 5, 2018
End Date
December 13, 2019
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
niversity of Newcastle

Eligibility Criteria

Inclusion Criteria

  • •Inclusion criteria for T1D:
  • •Age 30 – 80 years old
  • •T1D diagnosed before 18 years of age
  • •No advanced diabetes complications such as blindness or deafness
  • •Not hospitalised for severe glycemic events in the last 3 months
  • •Inclusion criteria for control group:
  • •No T1D or T2D diagnosis and HbA1c \<6\.5%
  • •Not taking medication for hypertension and cholesterol

Exclusion Criteria

  • •Not fluent in reading and writing in English
  • •No detectable transcranial Doppler (TCD) ultrasound signal in the middle cerebral artery on either side.
  • •Liver or kidney disease
  • •Malignant cancer
  • •Excessive alcohol intake (\>15 drinks per week)
  • •Neurological conditions including stroke, TIA, major depression, multiple sclerosis, Parkinson’s disease or dementia or mild cognitive impairment.
  • •Unwilling to provide a blood sample

Outcomes

Primary Outcomes

Not specified

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