Postprandial Lipid Metabolism in Patients With Hypertriglyceridemia and Normo-lipidemic Controls: Medium Chain Fatty Acids (MCT) in Comparison to Long-chain, Saturated Fatty Acids (SFA) and Mono-unsaturated Fatty Acids (MUFA)
Not Applicable
Completed
- Conditions
- Hypertriglyceridemia
- Interventions
- Other: MCTOther: SFAOther: MUFA
- Registration Number
- NCT03846908
- Lead Sponsor
- Ludwig-Maximilians - University of Munich
- Brief Summary
Postprandial lipid metabolism will be evaluated in patients with hypertriglyceridemia and normo-lipidemic controls; different fats will be used (saturated fatty acids, mon-unsaturated fatty acids and medium chain fatty acids) for the oral fat challenge.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 13
Inclusion Criteria
- hypertriglyceridemia (150 mg/dl-900 mg/dl)
Exclusion Criteria
- Lipid lowering drugs or indication for Lipid lowering drugs
- LDL-cholesterol > 190 mg/dl
- Diabetes mellitus
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description MCT MCT subjects start with MCT fat load MCT SFA subjects start with MCT fat load MUFA MCT subjects start with MUFA fat load MCT MUFA subjects start with MCT fat load MUFA MUFA subjects start with MUFA fat load SFA MCT subjects start with SFA fat load SFA SFA subjects start with SFA fat load SFA MUFA subjects start with SFA fat load MUFA SFA subjects start with MUFA fat load
- Primary Outcome Measures
Name Time Method postprandial hypertriglyceridemia 8 hours after fat meal area under the curve following oral fat load
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Munich
🇩🇪Munich, Germany