To Compare Effect of Erector spinae Block on Neutrophil Lymphocyte Ratio in patients undergoing On Pump CABG
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 132
- 试验地点
- 1
- 主要终点
- Decreased NLR in Erector spinae block group compared to opioid group
研究概览
简要总结
Introduction:
In cardiac surgery, owing to surgical manipulation, pain is considered severe. Inflammation and pain are interrelated, Neutrophil-lymphocyte ratio (NLR) Predicts the surgery induced inflammation in cardiac surgery patients. Regional anesthesia techniques modulate the inflammatory response as a result of surgical injury with various mechanisms at different levels This study aimed to investigate the effects of ESP block employed for postoperative analgesia in cardiac surgery on surgery-induced inflammation using NLR.
Methodology:
Patients underwent either an ESP block or a conventional analgesia technique for CABG surgery (20 patients in each arm). ESPB infusion was continued till post op day 2. The NLR ratio and VAS scores were sequentially noted till 48 hr postoperatively. MV duration and intensive care unit (ICU) length of stay was also noted.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •All adult patients.
排除标准
- •Severe LV dysfunction,pre-existing coagulopathy,patient refusal,pre-existing site infection ,patient preoperatively on ventilator.
结局指标
主要结局
Decreased NLR in Erector spinae block group compared to opioid group
时间窗: Postoperative Day 0, 1 and 2
次要结局
- Decreased PLR in Erector spinae block group compared to opioid group(Pod 1 ,2)
研究者
Dr Pulipaka Sai Dheeraj
Resident Anaesthesia