Effectiveness of Physical Exercise With Flow Restriction on the Diameter and the Flow of the Blood Vessels of the Forearm in Chronic Kidney Disease: a Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 主要终点
- Increasing the diameter of the cephalic vein
研究概览
简要总结
The aim of this study is to analyze the effectiveness of physical exercise with blood flow restriction on the diameter and the flow of vessels, muscle strength and circumference of the forearm in patients with CKD prior to making FAV.
详细描述
Definitions of goals
General Analyze the effectiveness of physical exercise with blood flow restriction on the diameter and the flow of vessels, muscle strength and circumference of the forearm in patients with CKD prior to making arteriovenous fistula.
Specific
- Draw the profile of patients with CKD as the clinical and laboratory features (hematocrit, hemoglobin, urea, creatinine) and glomerular filtration rate;
- Assess the vascular conditions, muscle strength and circumference of the upper limb of the non-dominant forearm before and after exercise programs;
- Compare the physical exercise programs with and without blood flow restriction vascular changes, muscle strength and circumference of the non-dominant arm;
- To correlate the diameter measurements and blood flow to the muscle strength and circumference of the upper limb not dominant.
Methodology Study design This is a randomized controlled trial, blind and endowed with allocation concealment to be developed in Physiotherapy clinic and Nephrology at the Clinical Hospital, Federal University of Pernambuco and Cardiopulmonary Physiotherapy Laboratory in the Department of Physical Therapy, Federal University of Pernambuco, the From December 2015 to November 2016, following approval of the Committee of Ethics in Research / the Health Sciences Center.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with Chronic Kidney Disease (CKD) stage 4 or 5;
- •In conservative or dialysis treatment;
- •Medical indication of arteriovenous fistula as an achievement of HD.
排除标准
- •Cognitive impairment or changes that hinder understanding, realization of activities and interpretation of the issues;
- •a history of making FAV in both upper limbs or some other type of vascular surgery in upper limbs, with some type of vascular access in upper limbs or in nearby regions;
- •to develop some kind of manual work with heavy loads;
- •Trauma-orthopedic lesions in the cervical, shoulder, elbow, wrist and untreated (or) hand;
- •Signs of thrombophlebitis and hypoplasia / agenesis of the upper limbs.
结局指标
主要结局
Increasing the diameter of the cephalic vein
时间窗: 8 weeks of training for each patient
Increasing the diameter of the cephalic vein of at least 0.22 mm
次要结局
- Increasing the diameter of the radial artery(8 weeks of training for each patient)
- Radial artery blood flow(8 weeks of training for each patient)
- Forearm Circumference(8 weeks of training for each patient)
- Muscle strength of the forearm(8 weeks of training for each patient)
研究者
Jefferson Belarmino Nunes Barbosa
postgraduate in integrated multidisciplinary residency in health, concentration area in physical therapy in nephrology
Universidade Federal de Pernambuco